Manisha Tiwari Selected Research

Piperazine

4/2024	Multitarget action of Benzothiazole-piperazine small hybrid molecule against Alzheimer's disease: In silico, In vitro, and In vivo investigation.
5/2020	Development of novel N-(6-methanesulfonyl-benzothiazol-2-yl)-3-(4-substituted-piperazin-1-yl)-propionamides with cholinesterase inhibition, anti-β-amyloid aggregation, neuroprotection and cognition enhancing properties for the therapy of Alzheimer's disease.
1/2017	Novel Triazole-Piperazine Hybrid Molecules Induce Apoptosis via Activation of the Mitochondrial Pathway and Exhibit Antitumor Efficacy in Osteosarcoma Xenograft Nude Mice Model.
3/2015	Synthesis, biological evaluation and molecular docking study of novel piperidine and piperazine derivatives as multi-targeted agents to treat Alzheimer's disease.

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Manisha Tiwari Research Topics

Disease

12	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 03/2015
8	Neoplasms (Cancer) 01/2023 - 09/2008
6	Seizures (Absence Seizure) 12/2018 - 03/2015
4	Memory Disorders (Memory Loss) 04/2024 - 09/2018
2	Epilepsy (Aura) 01/2021 - 09/2018
2	Cognitive Dysfunction 10/2016 - 09/2011
2	Status Epilepticus (Complex Partial Status Epilepticus) 05/2016 - 04/2016
2	Body Weight (Weight, Body) 09/2011 - 07/2008
1	Lung Neoplasms (Lung Cancer) 12/2024
1	Neoplasm Metastasis (Metastasis) 01/2023
1	Breast Neoplasms (Breast Cancer) 11/2021
1	Carcinoma (Carcinomatosis) 11/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2021
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2021
1	Dementia (Dementias) 01/2020
1	Radiation Injuries (Radiation Sickness) 01/2017
1	Fibrosis (Cirrhosis) 01/2017
1	Vitiligo 01/2017
1	Pneumonia (Pneumonitis) 01/2017
1	Osteosarcoma (Osteogenic Sarcoma) 01/2017
1	Pancreatic Neoplasms (Pancreatic Cancer) 10/2016
1	Neuroblastoma 10/2016
1	Hypoxia (Hypoxemia) 03/2016
1	Drug Resistant Epilepsy 01/2016
1	Epileptic Syndromes 01/2016
1	Vitamin B Deficiency 11/2015
1	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2015
1	Hypertension (High Blood Pressure) 09/2012
1	Amnesia (Dissociative Amnesia) 09/2012
1	Cardiovascular Diseases (Cardiovascular Disease) 07/2008
1	Hyperhomocysteinemia 11/2007
1	Atherosclerosis 11/2007
1	Hyperbilirubinemia 01/2005

Drug/Important Bio-Agent (IBA)

7	Scopolamine (Hyoscine)FDA Link 04/2024 - 09/2011
6	LigandsIBA 04/2024 - 03/2015
4	PiperazineIBA 04/2024 - 03/2015
4	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021 - 01/2016
3	Amyloid (Amyloid Fibrils)IBA 05/2020 - 10/2015
3	HomocysteineIBA 11/2015 - 11/2007
3	Cholinergic Agents (Cholinergics)IBA 10/2015 - 09/2012
2	benzothiazoleIBA 04/2024 - 05/2020
2	SulfonamidesIBA 01/2021 - 12/2018
2	Pentylenetetrazole (Metrazol)IBA 01/2021 - 09/2018
2	Cholinesterases (Cholinesterase)IBA 05/2020 - 01/2016
2	MetalsIBA 11/2018 - 10/2015
2	diallyl disulfide (diallyl disulphide)IBA 08/2017 - 10/2015
2	Neuroprotective AgentsIBA 10/2016 - 09/2011
2	Pilocarpine (Ocusert)FDA LinkGeneric 05/2016 - 04/2016
2	3-Mercaptopropionic Acid (3 Mercaptopropionic Acid)IBA 05/2016 - 04/2016
2	thiosemicarbazideIBA 05/2016 - 04/2016
2	AntioxidantsIBA 01/2016 - 10/2015
1	SilverIBA 12/2024
1	Phosphotransferases (Kinase)IBA 01/2023
1	tyrosine receptor (receptor, tyrosine)IBA 01/2023
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2023
1	AnnexinsIBA 11/2021
1	Fluorescein-5-isothiocyanate (FITC)IBA 11/2021
1	CrizotinibIBA 11/2021
1	isothiocyanic acidIBA 11/2021
1	5,5',6,6'- tetrachloro- 1,1',3,3'- tetraethylbenzimidazolocarbocyanineIBA 11/2021
1	diacetyldichlorofluoresceinIBA 11/2021
1	Protein Isoforms (Isoforms)IBA 01/2021
1	Photosensitizing Agents (Photosensitizers)IBA 12/2020
1	carbazoleIBA 01/2020
1	benzocycloheptapyridineIBA 08/2019
1	quinolineIBA 11/2018
1	Urea (Carbamide)FDA LinkGeneric 09/2018
1	TriazinesIBA 08/2017
1	Donepezil (Aricept)FDA LinkGeneric 01/2017
1	Melanins (Melanin)IBA 01/2017
1	CytokinesIBA 01/2017
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2017
1	TriazolesIBA 01/2017
1	esculetinIBA 10/2016
1	CoumarinsIBA 10/2016
1	CaspasesIBA 10/2016
1	Proteins (Proteins, Gene)FDA Link 10/2016
1	compound 30IBA 05/2016
1	gamma-Aminobutyric Acid (GABA)IBA 04/2016
1	trans-sodium crocetinate (crocetin)IBA 04/2016
1	Carbonic Anhydrase IXIBA 03/2016
1	Biomarkers (Surrogate Marker)IBA 11/2015
1	piperidineIBA 03/2015
1	Phenobarbital (Luminal)FDA Link 03/2015
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 09/2012
1	Enalapril FDA LinkGeneric 09/2012
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 09/2008
1	CarcinogensIBA 09/2008
1	DDTIBA 09/2008
1	Methionine (L-Methionine)FDA Link 07/2008
1	LipidsIBA 07/2008
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2008
1	CholesterolIBA 11/2007
1	Riboflavin (Vitamin B2)FDA LinkGeneric 01/2005
1	MetalloporphyrinsIBA 01/2005

Therapy/Procedure

4	Therapeutics 05/2020 - 03/2016
1	Chemoprevention 12/2024
1	Photochemotherapy (Photodynamic Therapy) 12/2020
1	Oral Administration 08/2018
1	Phototherapy (Light Therapy) 01/2005